Hippocampal abnormalities and seizure recurrence after antiepileptic drug withdrawal
- 11 July 2006
- journal article
- research article
- Published by Wolters Kluwer Health in Neurology
- Vol. 67 (1) , 134-136
- https://doi.org/10.1212/01.wnl.0000223350.08394.06
Abstract
The authors performed hippocampal volumetry and T2 relaxometry in 84 consecutive patients with partial epilepsy from a protocol for antiepileptic drug (AED) withdrawal after at least 2 years of seizure control. Seizure recurrence after AED withdrawal was more frequent among patients with hippocampal atrophy and abnormal hippocampal T2 signal.Keywords
This publication has 8 references indexed in Scilit:
- Is low antiepileptic drug dose effective in long-term seizure-free patients?Arquivos de Neuro-Psiquiatria, 2003
- Clinical and Neuroimaging Features of Good and Poor Seizure Control Patients with Mesial Temporal Lobe Epilepsy and Hippocampal AtrophyEpilepsia, 2003
- Hippocampal atrophy and T2-weighted signal changes in familial mesial temporal lobe epilepsyNeurology, 2003
- The Prognosis for Control of Seizures with Medications in Patients with MRI Evidence for Mesial Temporal SclerosisEpilepsia, 1999
- Is the underlying cause of epilepsy a major prognostic factor for recurrence?Neurology, 1998
- Relapse following discontinuation of antiepileptic drugsNeurology, 1994
- Some Aspects of Prognosis in the Epilepsies: A ReviewEpilepsia, 1993
- MRI volumetric measurement of amygdala and hippocampus in temporal lobe epilepsyNeurology, 1993