Genetic mapping of thet-complex region on mouse chromosome 17 including theHybrid sterility-1 gene
- 1 June 1991
- journal article
- Published by Springer Nature in Mammalian Genome
- Vol. 1 (2) , 84-91
- https://doi.org/10.1007/bf02443783
Abstract
t-haplotypes occupy a region on chromosome (Chr) 17 which slightly overlaps the ends of theT-H-2 interval. The wild-type form of this 14 centi-Morgan (cM) region was mapped in a multilocus backcross (C57BL/10-T×C3H)F1×C57BL/10 using 15 DNA probes on Southern blots of the DNA extracted from 53 animals which were recombinants in theT-H-2 interval. Each recombinant was also progenytested to ascertain itsHybrid sterility-1 (Hst-1) genotype by crossing to PWB/Ph, aMus musculus-derived inbred strain. The limit of resolution of the cross was 0.27 cM. The map distances have been determined for the DNA loci in theT-H-2 interval and theHst-1 gene was mapped in close vicinity to theD17Rp17 locus.Keywords
This publication has 31 references indexed in Scilit:
- Mapping of the Sod-2 locus into the t complex on mouse chromosome 17Immunogenetics, 1988
- What do we know about speciation?Nature, 1988
- Allelic profile at 37 biochemical loci of two inbred strains of the house mouse derived from wild Mus musculus musculusLaboratory Animals, 1988
- Deletion and duplication of DNA sequences is associated with the embryonic lethal phenotype of the t9 complementation group of the mouse t complex.Genes & Development, 1987
- Genetic studies of three sibling species ofDrosophilawith relationship to theories of speciationGenetics Research, 1985
- Gene mapping within the T/t complex of the mouse. III: t-lethal genes are arranged in three clusters on chromosome 17Cell, 1984
- New human transforming genes detected by a tumorigenicity assay.Molecular and Cellular Biology, 1984
- A technique for radiolabeling DNA restriction endonuclease fragments to high specific activityAnalytical Biochemistry, 1983
- Hybrid Sterility Gene Located in the T/t-H-2 Supergene on Chromosome 17Published by Springer Nature ,1981
- LINKAGE IN MICE AND RATSGenetics, 1920