Cardiovascular effects of the aqueous extract of Moringa pterygosperma
- 1 February 1995
- journal article
- research article
- Published by Wiley in Phytotherapy Research
- Vol. 9 (1) , 37-40
- https://doi.org/10.1002/ptr.2650090109
Abstract
The aqueous extract of stem bark of Moriga pterygosperma (Family Moraingaceae) was investigated for its effect on various pharmacological parameters. In cardiovascular profile at lower concentrations (1–10 ng) it produced a dose dependent positive inotropic effect (n = 3, 1.29 ± 0.021 for 10 ng) and at higher concentrations (0.1–1 μg) a dose dependent negative inotropic effect (n = 3, 0.53 ± 0.033 for 1 μg) on the isolated frog heart. It also produced a dose dependent hypotensive effect on dog blood pressure (n = 3, 82 ± 0.98 for 20 mg/kg). It failed to elicit any effect on isolated guinea‐pig ileum, rat stomach fundus or frog rectus abdominis muscle.Keywords
This publication has 1 reference indexed in Scilit: