A case of melanotic sarcoma with widespread metastases involving all tissues, including the brain and the spinal cord, recently came under my observation. In view of the rarity of this disease with such widespread metastases, a report of the clinical and pathologic observations in my case may be of interest. REPORT OF CASE G. S., a well developed man aged 70, a cooper, reported to the dermatologic clinic of the Toronto General Hospital in April 1936. A dark brown mole had been present in the right axilla for thirty-five years. About one year prior to his visit to the hospital the lesion began to enlarge, became irritable and bled when rubbed. Apart from the mole the only complaint was of fatigue. Examination showed a raised hard purplish black mole in the right axilla, 2 cm. in diameter; immediately about the margin were smaller, elevated hard black nodules. Similar