24R,25‐Dihydroxyvitamin D stimulates creatine kinase BB activity in chick cartilage cells in culture
- 27 February 1984
- journal article
- Published by Wiley in FEBS Letters
- Vol. 167 (2) , 281-284
- https://doi.org/10.1016/0014-5793(84)80143-x
Abstract
In chick limb-bud cartilage cell cultures 24R,25-dihydroxycholecalciferol (24R,25(OH)2D3), but not 24S,25(OH)2D3, 1α,25(OH)2D3 or 25(OH)D3, stimulates the activity of the brain type (BB) isozyme of creatine kinase (EC 2.7.3.2), the ‘estrogen-induced protein’ first identified in rat uterus. Cultures treated with bromodeoxyuridine, in which cartilage formation in inhibited, show no stimulation of creatine kinase BB by 24R,25(OH)2D3.Keywords
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