Concise Review: Stem Cells As an Emerging Platform for Antibody Therapy of Cancer
Open Access
- 1 November 2010
- journal article
- review article
- Published by Oxford University Press (OUP) in The International Journal of Cell Cloning
- Vol. 28 (11) , 2084-2087
- https://doi.org/10.1002/stem.513
Abstract
Monoclonal antibodies are important tools for cancer therapy, however, three factors limit their effectiveness: toxicity, poor tumor penetration, and inability to cross the blood-brain barrier. This review discusses the emerging field of stem cell-mediated antibody delivery and how this approach may improve antibody therapy of cancer by overcoming these obstacles.Keywords
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