Anergy in jaundiced patients
Open Access
- 1 February 1988
- journal article
- research article
- Published by Oxford University Press (OUP) in British Journal of Surgery
- Vol. 75 (2) , 147-149
- https://doi.org/10.1002/bjs.1800750219
Abstract
A prospective study of delayed hypersensitivity was carried out in jaundiced patients. One hundred and nineteen subjects were studied. Fifty-nine were controls and sixty were patients with pancreatobiliary pathology and biliary tract obstruction. A Multitest technique was used to evaluate the delayed hypersensitivity response, classifying the subject into one of three groups: immunocompetent, relatively anergic and anergic. In the control group, 76 per cent of the subjects were immunocompetent as opposed to 17 per cent of the patients (P<0.001). Ten per cent of the control subjects and fifty-five per cent of the patients presented anergy (P<0.001). Amongst the patients no difference could be found in the index of anergy between malignant or benign pathology. A greater incidence of postoperative septic complications in anergic and relatively anergic patients was found. Our study indicates a relationship between jaundice and anergy.Keywords
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