DMPU: An Alternative to HMPT in Moth Sex Pheromone Synthesis
- 1 January 1988
- journal article
- research article
- Published by Georg Thieme Verlag KG in Synthesis
- Vol. 1988 (03) , 250-252
- https://doi.org/10.1055/s-1988-27534
Abstract
1,3-Dimethyl-2-oxo-hexahydropyrimidine (DMPU, or N,N′-dimethylpropyleneurea) is found to be a good substitute for the carcinogenic hexamethylphosphoric triamide (HMPT) as cosolvent in the alkylation of lithium 1-alkynides, key intermediates in moth sex pheromone synthesis.Keywords
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