Synthesis of Aminobisphosphonate
- 1 May 1996
- journal article
- research article
- Published by Taylor & Francis in Synthetic Communications
- Vol. 26 (10) , 2037-2043
- https://doi.org/10.1080/00397919608003560
Abstract
A new facile synthesis of aminobisphosphonate was reported. Dibenzylamine bisphosphonate (1) is prepared from dibenzylamine, triethyl orthoformate and diethyl phosphite. Deprotection by hydrogen transfer reaction and acid hydrolysis afforded aminobisphosphonate (2).Keywords
This publication has 2 references indexed in Scilit:
- ORGANISCHE PHOSPHORVERBINDUNGEN 75: Herstellung und Eigenschaften von Aminomethylendiphosphinaten und -diphosphonaten, RR1NCH[P(O)R2(OR3)]2und Derivaten1Phosphorus and Sulfur and the Related Elements, 1981
- Rapid, Selective Removal of Benzyloxycarbonyl Groups from Peptides by Catalytic Transfer HydrogenationSynthesis, 1976