Abstract
THE successful reproduction of any animal species depends upon an elegant, complex and precisely arranged sequence of biologic events. The environment in which these events occur is often poorly understood. Significant delay in their timing can result in the whole spectrum of sterility, infertility and congenitally anomalous offspring. Nowhere is the necessity for biologically precise timing more apparent than in the many factors surrounding fertilization of the mature oocyte.1 That this is so throughout the animal kingdom is made abundantly clear by the careful and excellent review of this important subject as a Medical Progress report by Lanman in this . . .

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