AGE SUSCEPTIBILITY TO FAMILIAL INFECTION IN RHEUMATIC FEVER
Open Access
- 1 April 1931
- journal article
- research article
- Published by American Society for Clinical Investigation in Journal of Clinical Investigation
- Vol. 10 (1) , 53-60
- https://doi.org/10.1172/jci100341
Abstract
In a selected population (99 members of 14 families in which 2 or more individuals had suffered with evidences of rheumatic fever), the disease spread particularly to the younger members of the family, and was largely distributed throughout the age group 5-12, reaching its peak at about the age of 7. Among children 5-12 yrs. old, who apparently had not previously suffered from any manifestations of the disease, rheumatic fever was acquired in association with familial exposure, at the rate of 25-35%. Among children 5-12 yrs. old, who had survived an initial attack, recurrences were noted in association with familial exposure at the rate of 35-60%, decreasing as age increased, but representing a markedly enhanced susceptibility during adolescence.This publication has 1 reference indexed in Scilit:
- THE SPREAD OF RHEUMATIC FEVER THROUGH FAMILIESJournal of Clinical Investigation, 1931