Systematic Evaluation of AAV Vectors for Liver directed Gene Transfer in Murine Models
Open Access
- 1 January 2010
- journal article
- Published by Elsevier in Molecular Therapy
- Vol. 18 (1) , 118-125
- https://doi.org/10.1038/mt.2009.246
Abstract
No abstract availableKeywords
This publication has 24 references indexed in Scilit:
- Naturally occurring singleton residues in AAV capsid impact vector performance and illustrate structural constraintsGene Therapy, 2009
- Adeno-Associated Virus-Mediated Gene Transfer to Nonhuman Primate Liver Can Elicit Destructive Transgene-Specific T Cell ResponsesHuman Gene Therapy, 2009
- Identification of the murine firefly luciferase-specific CD8 T-cell epitopesGene Therapy, 2009
- Vaccines Based on Novel Adeno-Associated Virus Vectors Elicit Aberrant CD8+T-Cell Responses in MiceJournal of Virology, 2007
- Cross-Presentation of Adeno-Associated Virus Serotype 2 Capsids Activates Cytotoxic T Cells But Does Not Render Hepatocytes Effective Cytolytic TargetsHuman Gene Therapy, 2007
- Safe and efficient transduction of the liver after peripheral vein infusion of self-complementary AAV vector results in stable therapeutic expression of human FIX in nonhuman primatesBlood, 2006
- High-Level Transgene Expression in Nonhuman Primate Liver with Novel Adeno-Associated Virus Serotypes Containing Self-Complementary GenomesJournal of Virology, 2006
- Human immunoglobulin inhibits liver transduction by AAV vectors at low AAV2 neutralizing titers in SCID miceBlood, 2006
- Sustained correction of disease in naive and AAV2-pretreated hemophilia B dogs: AAV2/8-mediated, liver-directed gene therapyBlood, 2005
- Total correction of hemophilia A mice with canine FVIII using an AAV 8 serotypeBlood, 2004