Immunological Studies of Anthrax
Open Access
- 1 January 1962
- journal article
- Published by Oxford University Press (OUP) in The Journal of Immunology
- Vol. 88 (1) , 15-19
- https://doi.org/10.4049/jimmunol.88.1.15
Abstract
Summary: Levels of resistance to challenge with spores of a virulent strain of Bacillus anthracis were measured by means of an immunity index. The immunizing effect of protective antigen alone produced a level of resistance approximately 1000-fold greater than that of controls. The effect of protective antigen and a supplemental injection of live vaccine was 100,000,000-fold. Live vaccine alone produced only a 10- to 15-fold increase in resistance.Keywords
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