Klinefelter's syndrome in Sardinia
- 1 October 1986
- journal article
- Published by Wiley in Clinical Genetics
- Vol. 30 (4) , 276-284
- https://doi.org/10.1111/j.1399-0004.1986.tb00607.x
Abstract
265 hypogonadic Sardinian males, ascertained through military records of 600,000 conscripts approximately over the last thirty‐seven years, were screened for their sex chromatin phenotype by buccal mucosa smears and for their karyotypes from peripheral blood lymphocyte cultures. 158 (59.4%) showed a XXY karyotype without mosaicismo, 5 XX and 1 XXYY karyotypes. Seven sex chromatin negative males had Kallmann's syndrome. This report summarizes the genetic and clinical data recorded in this population sample as opposed to those reported from fertility clinics.Keywords
This publication has 4 references indexed in Scilit:
- An aetiological study of 290 XXY males, with special reference to the role of paternal ageHuman Genetics, 1984
- Additional pedigree supporting the frequent origin of XXYY from consecutive meiotic non-disjunction in paternal gametogenesis.Journal of Medical Genetics, 1979
- Prevalence of chromosome abnormalities among males examined for military serviceClinical Genetics, 1973
- Genetic characteristics of families of XO and XXY patients, including evidence of source of X chromosomes in 7 aneuploid patients.Journal of Medical Genetics, 1968