Graphical and statistical analysis of hyperbolic tight-binding inhibition
- 15 June 1987
- journal article
- research article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 244 (3) , 793-796
- https://doi.org/10.1042/bj2440793
Abstract
Equations are described for the analysis of enzyme-catalysed reactions in the presence of hyperbolic tight-binding inhibitors using both graphical and non-linear-regression methods. The general character of the equations allows the interpretation of several other kinetic mechanisms. As an example, the tight-binding hyperbolic non-competitive inhibition of human leucocyte elastase by a polysulphated glycosaminoglycan is analysed.This publication has 19 references indexed in Scilit:
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