DEMONSTRATION OF BACTERIOCIN ACTIVITY IN BOVINE AND BISON STRAINS OF PASTEURELLA-MULTOCIDA

  • 1 January 1977
    • journal article
    • research article
    • Vol. 38  (8) , 1183-1185
Abstract
Of 33 strains of P. multocida examined, 14 showed bacteriocin activity and 17 were susceptible to bacteriocin. The activity was increased by about 2-fold if the cultures were induced with UV radiation; no increase in bacteriocin activity was observed if the potential producer strains were induced with mitomycin C. The bacteriocin activity of potential producer strains was increased if CaCl2 was incorporated in the medium. The patterns of bacteriocin susceptibility indicate that these substances may ultimately contribute to a typing scheme for the species. An extrachromosomal genetic element was not detected when a potential producer strain was tested by the dye-buoyant density gradient method. Apparently the genetic material responsible for bacteriocin activity in P. multocida is located on the host chromosome.

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