An Autumn-Enhanced Mucotropic Action of Inhaled Terpenes and Related Volatile Agents

Publisher Website
Google Scholar
Abstract
Ten of eleven terpenes and related perfumes and flavouring agents given by inhalation augmented the volume output of respiratory tract fluid in urethanized rabbits at amounts which produced no or a barely detectable scent to the inhaled air. The mucotropic action tended to be less or to disappear at larger amounts which imparted a strong odour to the inhaled air and to be more evident in the autumn months of the year. In most instances, an increase in volume was accompanied by a decrease in the specific gravity of respiratory tract fluid. The bronchomucotropic action tended to be most evident following inhalation of camphanes such as fenchone, para-substituted phenols such as isosafrole, and open-ring terpenes such as citronellal. It was less evident or absent following inhalation of several derivatives of p-menthane such as dolcymene. The other volatile agents studied included anethole, carvone, cineole, ionone, linalyl acetate, phellandren, and Terpineol.

This publication has 0 references indexed in Scilit: