Palladium Asymmetric Allylic Alkylation of Prochiral Nucleophiles: Horsfiline
- 21 April 2006
- journal article
- letter
- Published by American Chemical Society (ACS) in Organic Letters
- Vol. 8 (10) , 2027-2030
- https://doi.org/10.1021/ol060298j
Abstract
The asymmetric synthesis of the oxindole alkaloid horsfiline is described. A palladium-catalyzed asymmetric allylic alkylation (AAA) is used to set the spiro(pyrrolidine-oxindole) stereogenic center.Keywords
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