Bispectral Analysis Of The Eeg In Developing Rats

Abstract
Bispectral analysis was applied to the electroencephalogram (EEG) recorded from the frontal cortex and hippocampus of the rat brain to examine the presence of quadratic phase coupling, as well as its deviation from Gaussian distribution during different vigilance states. Bispectra of these EEGs were computed for normally developing rats at different ages. At almost all ages it was found that significant phase coupling occurred within the hippocampal formation during REM sleep between the frequency components associated with theta rhythm. It was also observed that deviations from Gaussianity of the cortical EEGs follow a consistent ordering with cortical EEGs recorded during slow wave sleep having greater deviations from Gaussianity than quiet waking and REM sleep.

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