An Allenic Pauson−Khand-Type Reaction: A Reversal in π-Bond Selectivity and the Formation of Seven-Membered Rings
- 1 May 2002
- journal article
- Published by American Chemical Society (ACS) in Organic Letters
- Vol. 4 (11) , 1931-1934
- https://doi.org/10.1021/ol025955w
Abstract
Treatment of alkynyl allenes with [Rh(CO)2Cl]2 results in a formal [2 + 2 + 1] cycloaddition reaction. This reaction occurs with complete regioselectivity for a variety of substrates affording only 4-alkylidene cyclopentenones in good yields. Moreover, seven-membered rings have been prepared in high yields.Keywords
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