Dysfunctional Telomeres at Senescence Signal Cell Cycle Arrest via Chk2
- 12 October 2004
- journal article
- Published by Taylor & Francis in Cell Cycle
- Vol. 3 (10) , 1217-1220
- https://doi.org/10.4161/cc.3.10.1167
Abstract
Loss of telomere integrity can have two outcomes with opposite predicted effects on tumorigenesis. On the one hand, shortened telomeres in normal cells may trigger cell cycle arrest, leading to tum...Keywords
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