DEFECT OF ALTERNATIVE PATHWAY OF COMPLEMENT

  • 1 January 1977
    • journal article
    • research article
    • Vol. 27  (1) , 30-33
Abstract
The sera of patients, defective at opsonization for yeast phagocytosis, fix hemolytic complement poorly following incubation with the alternative pathway complement activators, inulin and bacterial [Escherichia coli] endotoxin. This suggests that the defect lies early in the alternative pathway of complement.