Puberty Onset in Males and Females Fed a High Fat Diet

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Abstract
Balanopreputial separation and vaginal opening and ovulation were observed in male and female rats as markers of sexual maturation. Animals fed a high fat diet containing the same protein content as a low fat diet showed normal pubertal onset. Both males and females fed a diet reduced in protein consisting of a mixture of dry chow and Crisco in a ratio of 2:1 showed delayed pubertal onset although their total daily caloric intake was similar to the animals fed a high fat diet with adequate protein. Puberty onset in both males and females is sensitive to changes in dietary intake.