Selection of a Mobile Phase Optimization Technique in High Performance Liquid Chromatography
- 1 March 1986
- journal article
- Published by Oxford University Press (OUP) in Journal of Chromatographic Science
- Vol. 24 (3) , 89-94
- https://doi.org/10.1093/chromsci/24.3.89
Abstract
A procedure is described for the selection of a liquid chromatographic mobile phase optimization scheme. The selection is based upon construction of three-point capacity factor vs. solvent composition diagrams, and proceeds from simple to complex mobile phases. Economy of experimental data is emphasized.Keywords
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