Plasma High-Density Lipoproteins

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Abstract
WHY all the recent excitement about highdensity lipoproteins (HDL)? Because of the strong inverse relation between plasma levels of HDL and mortality from cardiovascular disease.1,2 Increased serum levels of HDL protect against atherosclerosis, and decreased levels predispose to it.3 In this review, we discuss the measurement and normal levels of HDL, their chemical composition, the properties of the molecules making up HDL and our view of the structure of different HDL particles. The present evidence suggests that HDL or its precursors are produced by both the intestine and the liver. Further-more, HDL precursors are both directly secreted into plasma . . .