PILOCARPINE MEDICATION IN OPEN‐ANGLE GLAUCOMA

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Abstract
Two modes of topical pilocarpine therapy were applied to 16 patients with open-angle glaucoma. A pilocarpine drop medication (2% solution 4 times daily) was compared to a constant and continuous supply of pilocarpine by a therapeutic delivery system (Ocusert P-40). The pressure reducing efficiency was studied in the morning and in the following 4 h period of an ordinary drop medication regimen. The results indicate about equal pressure reducing properties in both high and low pre-treatment pressure values. Compared to pilocarpine drops, a statistically significant lower pressure was observed in the morning after the Ocusert unit, especially in glaucomatous eyes with high pre-treatment pressure.