Biology of regional body fat distribution: Relationship to non‐insulin‐dependent diabetes mellitus
- 1 March 1989
- journal article
- review article
- Published by Wiley in Diabetes/Metabolism Research and Reviews
- Vol. 5 (2) , 83-109
- https://doi.org/10.1002/dmr.5610050202
Abstract
Our studies support the view that body fat distribution and the accompanying metabolic abnormalities could be exacerabated by variability in the androgenic/estrogenic balance. Sensitivity to the androgenic milieu might be initiated by an early developmental aberration in sexual dimorphism. The possible direct and indirect sites of interaction between androgenic activity and the abnormal metabolic pathways in upper body obesity are summarized in Figure 19.Keywords
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