Use of Membrane Proteins from Salmonella gallinarum for Prevention of Fowl Typhoid Infection in Chickens
- 1 October 1987
- journal article
- research article
- Published by JSTOR in Avian Diseases
- Vol. 31 (4) , 699-704
- https://doi.org/10.2307/1591019
Abstract
Outer membrane protein isolated from Salmonella gallinarum was examined at different concentrations with or without a mineral-oil adjuvant for its immunogenicity and protection against live challenge. A formalin-killed whole-cell bacterin of the same organism was used for comparison. The results suggested that membrane proteins from S. gallinarum give better protection than formalin-killed whole-cell bacterin. Addition of an oil adjuvant to the protein appeared to increase the efficiency of the vaccine. When protein was given to chickens at 400 .mu.g/100 g of live body weight, it produced 100% protection against oral challenge with S. gallinarum.This publication has 10 references indexed in Scilit:
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