Coinfection with Hepatitis C Virus and Human Immunodeficiency Virus: Virological, Immunological, and Clinical Outcomes
- 1 August 2009
- journal article
- review article
- Published by American Society for Microbiology in Journal of Virology
- Vol. 83 (15) , 7366-7374
- https://doi.org/10.1128/jvi.00191-09
Abstract
Infection with hepatitis C virus (HCV) is estimated to affect 2% of the world population (90) and is a leading cause of liver-related morbidity and mortality. Human immunodefi- ciency virus (HIV) is also a very important global public health problem, infecting about 33 million people worldwide (129). As the transmission routes are shared by both infections, coin- fection is not uncommon. In this review, we discuss the mag- nitude of the problem, the effect of infection with one virus on the transmission and natural history of the other, and the treatment issues unique to coinfected patients. EPIDEMIOLOGYKeywords
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