Analysis of the cytotoxic T cell response to H-Y in CBA/H mice.
Open Access
- 1 August 1981
- journal article
- research article
- Published by Oxford University Press (OUP) in The Journal of Immunology
- Vol. 127 (2) , 681-685
- https://doi.org/10.4049/jimmunol.127.2.681
Abstract
The dose response, kinetics, and target cell specificity of the H-Y immune Tc-cell response of fp-primed CBA/H mice was analyzed. Non-MHC genes were shown to influence responsiveness in fp-primed H-2k strains of mice. The possibility that dominant T-suppressor cells mask responsiveness in i.p. primed CBA/H mice was not confirmed in mixing experiments. Female spleen-adherent cells injected with male spleen cells i.p. elicited H-Y immune Tc-cell responses.This publication has 1 reference indexed in Scilit:
- PHYSIOLOGICAL FUNCTION OF MAJOR HISTOCOMPATIBILITY COMPLEX MACROMOLECULESTransplantation, 1979