The in-vivo-nerve response to direct Low-Energy-Laser Irradiation

Abstract
To study the in-vivo effects of direct Low-Energy Laser Irradiation (LELI) on the Peripheral Nervous System, the sciatic nerve in rats was surgically exposed, crushed and then subjected to the direct irradiation of either of two continuous-wave HeNe lasers — 0.3 mW or 17mW. We found that the 0.3 mW laser significantly boosts the electrical activity in both the injured and non-injured nerves. The temperature changes of the nerve were measured during irradiation, and no thermal effect was detected. These findings could have direct therapeutic applications in various surgical situations.