Metabolism of Arterial Tissue With Special Reference to Esterase and Lipase.

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Abstract
Summary Esterase was demonstrated in normal aortic tissue of dog, rabbit and man. Its activity was determined in various layers of the 3 aortic segments (arch, descending thoracic, abdominal) as well as in liver and serum. Absence of lipase, except for dog serum, was constantly demonstrated. Of the 3 aortic layers studied (innermost intimamedia, media, adventitia), the adventitia displayed the lowest activity, about l/6th that of the other two. Intima-media showed no difference in activity between the 3 aortic segments in dog, or between descending thoracic and abdominal in rabbit or man, whereas a higher activity was noted in rabbit's arch. A species difference seems to exist, aortic intima-media showing the lowest values in man, and highest in rabbit's arch. A species difference was also noted with regard to liver and serum, the former showing the highest activity in rabbit and lowest in dog, whereas serum showed similar activity in dog and man, and much greater in rabbit.

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