The effect of hydrocortisone on the concentration and synthesis of acid mucopolysaccharides in the rat gingiva
- 30 June 1970
- journal article
- Published by Wiley in Journal of Periodontal Research
- Vol. 5 (3) , 259-262
- https://doi.org/10.1111/j.1600-0765.1970.tb00726.x
Abstract
Treatment of adult male rats with hydrocortisone acetate in a dosis of 5 mg/Kg of body weight daily during 20 days produced a decrease in the concentration of hyaluronic acid, chondroitin‐6‐sulfate and heparin in gingiva. These effects are at least partially due to a decrease in the rate of synthesis of such compounds, as measured by incorporation of acetate‐C14 and sulfate‐S35 into mucopolysaccharides.Keywords
This publication has 5 references indexed in Scilit:
- Micro separation and determination of mammalian acidic glycosaminoglycans (mucopolysaccharides)Analytical Biochemistry, 1967
- Effects of Adrenalectomy upon Ascorbic Acid Concentration in Periodontal Tissues in Guinea PigsJournal of Dental Research, 1963
- A modified uronic acid carbazole reactionAnalytical Biochemistry, 1962
- Studies on the action of some anti-inflammatory agents in inhibiting the biosynthesis of mucopolysaccharide sulphatesBiochemical Pharmacology, 1961
- THE METABOLISM OF MUCOPOLYSACCHARIDES IN ANIMALS: THE EFFECT OF CORTISONE AND HYDROCORTISONE ON RAT SKIN1Endocrinology, 1957