FACTORS AFFECTING RIBOFLAVIN PRODUCTION BY ASHBYA GOSSYPII

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Abstract
A. gossypii biosynthesizes large amts. of riboflavin when propagated in certain media under conditions of submerged aerobic cultivation. A satisfactory medium is composed of glucose, corn steep liquor and animal stick liquor. The use of small quantities of young inocula, a minimum sterilization time, and an efficient means of aeration are ad-ditional factors of importance. Under favorable conditions the commercial production of riboflavin, either in concentrate or pure form, may be based on the use of A. gossypii.