THE ANALGESIC ACTION OF NORMORPHINE ADMINISTERED INTRACISTERNALLY TO MICE
- 1 September 1958
- journal article
- research article
- Published by Oxford University Press (OUP) in Journal of Pharmacy and Pharmacology
- Vol. 10 (1) , 80-85
- https://doi.org/10.1111/j.2042-7158.1958.tb10276.x
Abstract
The analgesic action of normorphine developed more rapidly than that of morphine and was, weight for weight, as great as that of morphine, and was as effectively antagonised by N-allylnormorphine when these drugs were administered intracisternally to mice. By this route, more than one molecule of N-allymonnoirphine was required to antagonise the action of one molecule of analgesic drug.Keywords
This publication has 3 references indexed in Scilit:
- Analgesics and their Antagonists: Some Steric and Chemical Considerations: PartJournal of Pharmacy and Pharmacology, 1956
- Synthetic Analgesics: Stereochemical ConsiderationsJournal of Pharmacy and Pharmacology, 1954
- STUDIES ON THE PHARMACOLOGY OF N-ALLYLNORMORPHINE1954