Personality Dimensions in First-Episode Psychoses

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Abstract
Objective: The authors compared the patterns and specificity of premorbid per- sonality dimensions in first-episode schizo- phrenia patients with those in patients with first-episode nonschizophrenia psy- choses and healthy comparison subjects. Method: A series of 63 patients with first- episode schizophrenia and related psy- chotic disorders, 34 patients with first-epi- sode nonschizophrenia psychoses, and 77 healthy comparison subjects were as- sessed with the Personality Disorder Evalu- ation, a semistructured interview schedule that measures personality dimensions. Results: Cluster A as well as cluster C dimensional scores—in particular, the avoidant personality score—were higher for the schizophrenia patients, and cluster B dimensional scores were higher for the patients with nonschizophrenia psychoses. Cluster C dimensional scores, particularly the avoidant personality score, were highly intercorrelated with all cluster A dimen- sional scores. Conclusions: The observed association between avoidant personality and schizo- phrenia supports the recent literature on the comorbidity of nonspectrum personal- ity disorders in schizophrenia. This associa- tion may be related to shared neurodevel- opmentally mediated impairments in social cognition in schizophrenia and some cluster C personality dimensions.

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