ANALYSIS OF AEROSOL DECAY DURING BREATH-HOLDING
- 1 September 1975
- journal article
- research article
- Published by Oxford University Press (OUP) in Annals of Occupational Hygiene
- Vol. 18 (2) , 161-172
- https://doi.org/10.1093/annhyg/18.2.161
Abstract
The decay in aerosol concentration in the human respiratory tract during breath-holding in single-breath inhalations was studied analytically. The calculations incorporate ideas on air flow and on aerosol deposition within the respiratory tract, proposed by DAVIES (1972). Models were developed for both the diffusion-controlled transport case and for the sedimentation-controlled transport case. Agreement between the calculations and the experimental data of Palmes and his collaborators, was acceptable when Weibel's model of the respiratory tract was used to define airway dimensions, but Davies' respiratory tract model resulted in calculated decay rates which were considerably lower than the experimental rates.Keywords
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