TOXOPLASMOSIS

1 March 1945

journal article
research article
Published by American Medical Association (AMA) in Archives of Ophthalmology (1950)

Vol. 33 (3) , 184-191
https://doi.org/10.1001/archopht.1945.00890150028003

Abstract

Toxoplasmosis is a recently recognized infectious disease in human beings. Four principal types have been reported: (1) a granulomatous encephalitis, usually of congenital origin and occurring in fetal or early infantile life; (2) an acquired acute encephalitis occurring in children; (3) an acquired acute disease resembling Rocky Mountain spotted fever occurring in adults; (4) a latent subclinical form occurring in adults. Sabin, in 1943,¹outlined the status of Toxoplasma, which was isolated by Nicolle and Manceaux from the gondi North African rodent in 1908²and by Splendore from the rabbit in Brazil in the same year. The parasite has been classified as a protozoon of the genus Toxoplasma. It has a wide geographic distribution and occurs in many species of animals, both wild and domestic. Sabin and Olitsky in 1937³found the parasite in guinea pigs and were able to transmit it through several animal passages. The

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