Recent insights into the mechanisms of Chlamydia entry
- 20 October 2005
- journal article
- review article
- Published by Hindawi Limited in Cellular Microbiology
- Vol. 7 (12) , 1714-1722
- https://doi.org/10.1111/j.1462-5822.2005.00627.x
Abstract
Chlamydia are widespread bacteria that grow in human and animal cells. They enter their host cell, establish an intracellular environment favourable for their multiplication and finally exit the host cell. A combination of host cell factors and of bacterial proteins contribute to pathogen entry. Recent advances have shed new light on the entry mechanism, following attachment. Here we review recent data concerning endocytosis, host cell signalling, proteins secreted by the bacteria, the actin cytoskeleton in entry and the involvement of small GTPasesKeywords
This publication has 53 references indexed in Scilit:
- ARF6 GTPase controls bacterial invasion by actin remodellingJournal of Cell Science, 2005
- Chlamydia pneumoniaeand atherosclerosisCellular Microbiology, 2004
- Role of lipid-mediated signal transduction in bacterial internalizationCellular Microbiology, 2003
- Bacterial virulence factors targeting Rho GTPases: parasitism or symbiosis?Trends in Cell Biology, 2003
- Bacterial Toxins That Modify The Actin CytoskeletonAnnual Review of Cell and Developmental Biology, 2002
- Chlamydia trachomatis cytotoxicity associated with complete and partial cytotoxin genesProceedings of the National Academy of Sciences, 2001
- Closing in on Chlamydia and its intracellular bag of tricksMicrobiology, 2000
- Rho GTPases and their effector proteinsBiochemical Journal, 2000
- FUNCTIONS OF LIPID RAFTS IN BIOLOGICAL MEMBRANESAnnual Review of Cell and Developmental Biology, 1998
- Characterization of Chlamydia trachomatis L2‐induced tyrosine‐phosphorylated HeLa cell proteins by two‐dimensional gel electrophoresisElectrophoresis, 1997