RADIOGRAPHIC HAND ABNORMALITIES IN 15 CASES OF CROUZON SYNDROME

  • 1 January 1982
    • journal article
    • research article
    • Vol. 2  (3) , 205-213
Abstract
Patients (15) with Crouzon syndrome were evaluated for abnormalities of hand bone length via metacarpophalangeal pattern profile analysis. Data from this group were compared to that from a normal control sample. A discriminant function, utilizing Z scores based on the lengths of 3 hand bones, was derived and distinguished between the 2 samples at a rate of 88.3%. The discriminant variables selected in the function represented hand bones that are prominently involved in ACS [acrocephalosyndactyly] type V and ACPS [acrocephalopolysyndactyly] type II, syndromes that feature craniofacial abnormalities not unlike those in Crouzon syndrome. The possibility of a common developmental mechanism affecting the hand skeleton in all 3 of these different conditions is raised.

This publication has 1 reference indexed in Scilit: