Haptoglobin 2-1 Bellevue, a haptoglobin beta-chain mutant.

1 April 1967

journal article
research article
Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences

Vol. 57 (4) , 920-924
https://doi.org/10.1073/pnas.57.4.920

Abstract

A new phenotype, Hp 2-1 Bellevue, is described. Data suggest that this phenotype is the result of an abnormal hpB chain, under the control of a locus separate from and not linked to Hp. The terms Bp, BpA, and BpB are suggested for the locus, the wild type, and the mutant alleles, respectively. Two additional phenotypes found in the members of the family are tentatively designated Hp 1-1 Bellevue and Hp 2-2 Bellevue. All these Hp types form Hb complexes with abnormal immunological properties, and all, except Hp 1-1 Bellevue, can be distinguished from the common phenotypes by starch gel and acrylamide electrophoresis.

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