Kinetic Determination of Trypsin with an Ammonia Gas-Sensing Membrane Electrode

Abstract
Trypsin activity is monitored in a simple kinetic method with an ammonia gas sensor. The method is based upon the hydrolysis of .alpha.-benzoyl-arginine amide resulting in the production of ammonia. Day-to-day precision range of .+-. 1.9% to 4.4% and a within-run precision range of .+-. 1.8% to 4.2% were measured for the working range of 0.5-20 .mu.g/ml-1 trypsin. An average of 97 .+-. 3.4% added trypsin was recovered from rat pancreatic juice in recovery experiments.

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