Sleep‐wake cycles in multi‐infarct dementia and dementia of the Alzheimer type

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Abstract
We monitored by actigraphs minute-by-minute activity of 10 patients with multi-infarct dementia (MID), 15 patients with dementia of the Alzheimer type (DAT), and 11 control volunteers for eight consecutive 24-hour periods to assess sleep-wake cycles and sleep quality. MID patients had disrupted sleep-wake cycles associated with decreased sleep quality. In contrast, ambulatory DAT patients maintained a relatively normal sleep-wake cycle that did not differ significantly from controls. There was no corrrelation between the severity of intellectual deterioration and the degree of sleep-wake cycle disintegration in either group of dementia patients.

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