NON-IDENTICAL REACTION OF UNDISSOCIATED HCG AND HCG-β SUBUNIT WITH ANTI-HCGβ SERUM
- 1 October 1975
- journal article
- Published by Oxford University Press (OUP) in Acta Endocrinologica
- Vol. 80 (2) , 374-379
- https://doi.org/10.1530/acta.0.0800374
Abstract
Based on gel-filtration experiments, estimates of the content are given of undissociated human chorionic gonadotrophin (HCG) and HCG-β subunit in HCG preparations. Radioimmunoassay of three HCG preparation using an antiserum against HCG-β subunit showed that the slope of displacement curves was dependent on the ratio of HCG-β subunit to undissociated HCG, the slope being steeper (negative) with increasing ratio. The implication of this observation on the choice of a suitable standard for HCG-β radioimmunoassay is discussed.Keywords
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