Increase of Plasma TSH Concentration Following Injection of Purified Hypothalamic TRF
- 1 November 1965
- journal article
- research article
- Published by The Endocrine Society in Endocrinology
- Vol. 77 (5) , 792-796
- https://doi.org/10.1210/endo-77-5-792
Abstract
A purified preparation of TSH [thyroid-stimulating hormone]-releasing factor (TRF), specific activity 30 U/ml, of sheep hypothalamus origin, elevates the levels of circulating plasma TSH from 21 to 197 mU/100 ml in 3 min. following intravenous injection in normal animals; even though less marked in amplitude, the same effect is seen in thyroidectomized animals. The material has no effect in hypophysectomized animals.This publication has 3 references indexed in Scilit:
- Further Purification of TSH-Releasing Factor (TRF) from Sheep Hypothalamic Tissues, with Observations on the Amino Acid Composition.Experimental Biology and Medicine, 1965
- On a Method for Calculation and Analysis of Results in the McKenzie Assay for Thyrotropin (TSH).Experimental Biology and Medicine, 1964
- THE BIOASSAY OF THYROTROPIN IN SERUM1Endocrinology, 1958