Adjuvant Chemotherapy in Ewing’s Sarcoma Patients

Abstract
At the Istituto Nazionale Tumori of Milan 60 patients with clinically localized Ewing’s sarcoma were treated during 1965–1978 according to three different protocols. From 1965–1971, 18 patients received almost exclusively local therapy and 17 of 18 (94%) relapsed in a median time of 6 months. From 1971–1978 adjuvant chemotherapy according to two different drug schedules was employed after radiotherapy. Twenty-five of 42 (59%) are surviving and relapse-free at this time (follow-up 20-101 months).

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