Consequences of hormone-induced desensitization of adenylate cyclase in intact cells
- 15 April 1980
- journal article
- research article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 188 (1) , 169-174
- https://doi.org/10.1042/bj1880169
Abstract
A hypothesis on the role of the hormone-induced desensitization of adenylate cyclase using human lung WI-38 cells as a model is proposed. The desensitization process could provide the cell with a highly efficient cyclic[c]AMP system for transmitting hormone stimulus without requiring a large energy consumption. Theoretical considerations show that in fact the desensitization phenomenon apparently allows the cAMP system to present a good compromise between the efficiency and economy requirements of the cells.This publication has 9 references indexed in Scilit:
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