A study of yeast surface antigens by agglutination inhibition
- 1 January 1964
- journal article
- Published by Oxford University Press (OUP) in Medical Mycology
- Vol. 3 (4) , 288-300
- https://doi.org/10.1080/00362176485190511
Abstract
Agglutination inhibition has been compared to quantitative precipitation in an immunochemical study of yeast polysaccharides. Mannans extracted from Candida albicans Groups A and B, C. stellatoidea, C. tropicalis, and Saccharomyces cerecisiae were used as agglutinin inhibiting or precipitating antigens. As a rule agglutinin inhibition was more sensitive than quantitative precipitation but not with every antiserum-polysaccharide combination. Agglutinin-inhibition offers a method whereby the polysaccharide antigen may be studied in situ but not all of the limitations or applications of the procedure have been elucidated. Au cours d'une étude immunochimique des polyosides de levures, on compare l'inhibition de l'agglutination et la précipitation quantitative. Des mannanes extraits de Candida albicans groupes A et B, de C. stellatoidea, C. tropicalis et Saccharomyces cerevisiae sont utilisés comme antigenes précipitants ou inhibiteurs d'agglutinines. D'une façon générale, l'inhibition des agglutinines est plus senible que la précipitation quantitative mais ceci n'est pas vrai pour toutes les combinaisons antisérum-polyoside. L'inhibition des agglutinines constitue une méthode permettant d'étudier l'antigène polyosidique in situ mais les limites de cette méthode, non plus que toutes ses applications ne sont élucidées.Keywords
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