Treatment of rheumatoid arthritis with ornidazole. A randomized, double-blind, placebo-controlled study

Abstract
Sir, In many previous studies, rheumatoid arthritis (RA) has been found at high frequencies in individuals with periodontitis, and RA resembles periodontitis in many pathological aspects [1, 2]. HLA-DR4 tissue antigens are found at high frequencies both in patients with periodontitis and in those with RA. HLA-DR4 tissue antigens and their subtypes are directly associated with each disease [3, 4].