Design of Potent Inhibitors for Human Brain Memapsin 2 (β-Secretase)

This publication has 15 references indexed in Scilit:

• Human aspartic protease memapsin 2 cleaves the β-secretase site of β-amyloid precursor protein
  Proceedings of the National Academy of Sciences, 2000
• Purification and cloning of amyloid precursor protein β-secretase from human brain
  Nature, 1999
• Identification of a Novel Aspartic Protease (Asp 2) as β-Secretase
  Molecular and Cellular Neuroscience, 1999
• β-Secretase Cleavage of Alzheimer's Amyloid Precursor Protein by the Transmembrane Aspartic Protease BACE
  Science, 1999
• Cellular mechanisms of β-amyloid production and secretion
  Proceedings of the National Academy of Sciences, 1999
• The cell biology of β-amyloid precursor protein and presenilin in Alzheimer's disease
  Trends in Cell Biology, 1998
• Transition-State Mimetics for HIV Protease Inhibitors: Stereocontrolled Synthesis of Hydroxyethylene and Hydroxyethylamine Isosteres by Ester-Derived Titanium Enolate Syn and Anti-Aldol Reactions
  The Journal of Organic Chemistry, 1998
• [18] Design of symmetry-based, peptidomimetic inhibitors of human immunodeficiency virus protease
  Published by Elsevier ,1994
• [17] Design of tight-binding human immunodeficiency virus type 1 protease inhibitors
  Published by Elsevier ,1994
• Iodination of aryltrimethylsilanes. A mild approach to (iodophenyl)alanine
  The Journal of Organic Chemistry, 1986